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A series of placebo-controlled, randomized, double-blind clinical trials investigating intravenous or intranasal administration of GSH showed improvements in motor symptoms, but these improvements lacked statistical significance compared to placebo (203205)

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Future research could focus on optimizing the treatment plan and achieving more precise and personalized treatment with multiple targets in multiple aspects

Tobacco Etch Virus (TEV) Protease TEV protease is a cysteine protease from Tobacco Etch Virus that recognizes the ENLYFQS/G consensus and cleaves with high sequence specificity, enabling precise tag removal with minimal residual amino acids (often only the natural N-termial residue) [160]