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HepG2 cells were co-transfected with human PPAR (, /, or )/RXR and MRP3 promoter constructs, then treated with PPAR agonists for 24 hours to determine the effects of PPAR agonists on MRP3 transactivation

higher-risk conditions include diets restricted in fruits and vegetables, smoking, and drug and alcohol abuse

SDO variants: Expedited, segmented and block transfer The CANopen SDO protocol specifies 3 different transfer methods: 1: Expedited transfer This transfers the full payload in a single initialization/confirmation flow between the client and server, ideal for small 1-4 byte data payloads 2: Segmented transfer This involves an initialization/confirmation step after which segments of up to 7 data bytes can be transferred (each segment requiring a confirmation message) 3: Block transfer This is useful for large data transfers

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Murakami S, Suzuki T, Harigae H, Romeo PH, Yamamoto M, Motohashi H (2017) NRF2 activation impairs quiescence and bone marrow reconstitution capacity of hematopoietic stem cells