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The FDA has flagged BPC-157 because of risks like immunogenicity (it could trigger immune reactions), peptide impurities, and lack of human safety data

BPC-157 occupies a complex regulatory space

Not every patient achieves the weight loss targets they are hoping for, and a meaningful proportion of patients even on maximum doses do not reach the 1520% body weight reduction that clinical guidelines increasingly use as a benchmark for meaningful metabolic benefit

Yang S, Jin H, Zhu Y, Wan Y, Opoku EN, Zhu L, et al

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TB-500 for Cardiovascular Health Preliminary studies suggest that TB-500 may have positive effects on cardiovascular health