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If the balance is broken by the accumulation of iron in macrophages, the unregulated iron export will cause tissue and even systematic iron overload, which creates opportunities for the occurrence of ferroptosis in tissue cells

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The compounds (and the OD 600 nm reached) of these positive hits included Cianidanol (OD 600 nm =1), Juglone (OD 600 nm =0.66), Deoxycholic acid (OD 600 nm =0.89), Carbenoxolone (OD 600 nm =0.58), Gossypin (OD 600 nm =0.77)(Figure S7)