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The litigation also engaged ANR in the fight over Proposition 99

These patterns, resulting from ROS-induced DNA damage and imperfect repair, indicate that chronic oxidative stress leaves a lasting genomic imprint even before transformation occurs

[PubMed: 6849345] Holt PG

Also, the registration of RID is strictly controlled in Korea, and the accuracy of the RID database for UC and CD diagnoses has been previously validated.27 Second, since smoking information, including onset age, duration, and amount of smoking, depends on voluntary self-reporting, the response reliability may differ according to individual responders

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