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doi: 10.3389/fnut.2022.864358 Received 28 January 2022 Accepted 07 March 2022 Published 08 April 2022 Volume 9 - 2022 Edited by Javier Diaz-Castro, University of Granada, Spain Reviewed by Grard Lizard, Universit de Bourgogne, France

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Although the response rate of anti-IGF-1R in clinical trials was disappointing, there are several strong pieces of evidence in preclinical models that defined the ability of anti-IGF-1R mAb to block the growth and migration of breast cancer cells as therapeutic potencies