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Description

To examine the biological function of the HOP1LET7 interaction, we generated LET7(K59D), where a positively charged residue was changed to a negative charge

[DOI] [PubMed] [Google Scholar] 73.Svobodova A, Walterova D, Vostalova J

Paxinos,G.) 129-148 (Elsevier Academic Press, San Diego, 2004)

Molecular replacement using the MrBUMP pipeline (50) in CCP4 Cloud (51) gave a reasonable solution using PDB 4M0W (Crystal Structure of SARS-CoV papain-like protease C112S mutant in complex with ubiquitin (52)) with a TFZ of 12.0 and an initial R free of 47%