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death of heart muscle tissue due to an interruption in its blood supply Observational study - a human research study in which no experimental intervention or treatment is applied, and participants are simply observed over time Oxidative stress - a situation in which the production of reactive oxygen species exceeds the ability of an organism to eliminate or neutralize them Placebo - a chemically inactive substance Primary prevention - taking measures to prevent the onset of disease Randomized controlled trial - a human research study in which participants are assigned by chance alone to receive either an experimental agent (the treatment group) or a placebo (the control group) Reactive oxygen species (ROS) - highly unstable oxygen-containing compounds that react easily with nearby cellular structures, potentially causing damage Authors and Reviewers Originally written in May 2015 by: Giana Angelo, Ph.D

Li Y, Ks N, Byran G, Krishnamurthy PT

This technology may help improve absorption and bioavailability, potentially making the supplement more effective at lower doses

It also has antioxidant properties and thus has been used as a nutritional supplement in disease conditions like diabetes and nervous and heart problems

doi: 10.1016/j.immuni.2014.06.010 129 ZhouWYuXSunSZhangXYangWZhangJet al

use as directed on pack and consult a healthcare professional if pregnant, nursing, or managing a medical condition