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AOD-9604 eliminates this confound entirely, allowing researchers to study fat metabolism pathway contributions in isolation

Mechanistically, reduced shear stress after PHx exacerbates LSEC senescence through the activation of Notch signaling, which inhibit SIRT1 expression

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Biomarker-Guided Stratification as a Future tool NET-related biomarkersincluding citrullinated histone H3, MPODNA complexes, and cell-free dsDNAcould help identify high-NET phenotypes and inform therapy selection, though standardization and prospective clinical studies are still needed

In a study by Wadhwa et al

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