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Selenium supplementation is known to enhance cell growth inhibition and apoptotic signaling via various mechanisms

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Ferritinophagy is required for the induction of ferroptosis by the bromodomain protein BRD4 inhibitor (+)-JQ1 in cancer cells

In the hepatocytes, GCKR shuttles between the cytoplasm and nucleus and regulates de novo lipolysis by controlling the glucose influx

In addition, it is suggested that the regulation of cytoskeleton and cell proliferation by the addition of glutamate induces cell differentiation of normal LECs and decreases their opacity