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doi:10.1089/ars.2012.4644, PMID: 22530666 Franco R, Panayiotidis MI, Cidlowski JA (2007) Glutathione depletion is necessary for apoptosis in lymphoid cells independent of reactive oxygen species formation

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First, TAZ interacts with RORt to increase its transcriptional activity while competitively relieving Foxp3-mediated repression, thereby coordinately upregulating Th17-associated gene expression and promoting Th17 cell development

Stress axis regulation DSIP acts as what researchers call a "stress-limiting factor." It modulates the hypothalamic-pituitary-adrenal (HPA) axis, the hormonal cascade responsible for your body's stress response

This gives the medication time to disperse in the tissue