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The Lachnospiraceae and Clostridiaceae families showed significant changes after sub-lethal exposure in mice [139, 140]

and (iii) consequent aggravation of insulin resistance, deterioration of glucose homeostasis, and disruption of immunological equilibrium - ultimately precipitating multi-organ dysfunction

Further studies have identified microRNAs (miRNAs) as key post-transcriptional regulators of mitochondrial metabolism in CRC [9]

Similarly, PD and AD patients had lower-than-normal hK6 content in the SN region (Ogawa et al., 2000)

A review with modeling found that for antidepressants metabolized by CYP2D6, normal metabolizers (NMs) would require at least double the dose required by PMs, while cost analyses have associated PM status with not only higher ADRs but also with more drop outs from treatment (Chou et al., 2003

Degradation risk is more closely associated with sustained exposure to high heat, humidity, or improper long-term storage