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Due to the spatially close histidine-residue, the cysteine sulfhydryl group is particularly reactive and, in turn, can be readily regulated by oxidative or nitrosative stress [135] or become inactivated by alkylation reactions with reactive electrophiles, such as acrolein

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Anxiety relief is a documented pharmacological property of d-limonene, with published research on limonene's anxiolytic activity confirming the interaction with serotonin (5-HT1A) receptors and dopaminergic pathways that produce measurable anxiety reduction