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Nucleotide oxidation, DNA strand breakage, loss of bases and adduct formation are ROS-induced DNA modification can lead to mutations and DNA damage [90]

introduced a manifold learning algorithm followed by LDA, demonstrating a detection delay of 200400 ms and a detection accuracy exceeding 80% for the classification of motor intent in healthy individuals (Ren et al., 2014)

Glucocorticoid has a strong anti-inflammatory effect, which is suitable for the treatment of moderate and severe UC, and can significantly reduce the intestinal symptoms of UC, but it is not effective in stabilizing the condition of UC

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Notably, the effects of these pathways are not static