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The structures were determined using single-particle cryo-electron microscopy (cryo-EM), an advanced in vitro structural biology technique that allows visualization of protein complexes at near-atomic resolution

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For context, that is around half the width of Earth

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These internal timing systems integrate diverse environmental (e.g., light) and metabolic (e.g., food intake) stimuli to regulate biological activities, including sleep/wake, energy metabolism, hormonal and immune functions, and cell proliferation 1