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Conflicts of Interest The authors declare no conflicts of interest

Additionally, circulating CD38 + lymphocytes and plasmablasts were found to be elevated in SSc 23

It would likely involve establishing a baseline with each compound separately before attempting a very brief, low-dose combination phase to assess safety and tolerance

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Furthermore, tamoxifen-induced apoptosis was mediated via cancerous inhibitor of protein phosphatase 2A (CIP2A) /protein phosphatase 2A (PPA2) / phospho-Akt (p-Akt) cascade in MDA-MB-231, MDA-MB-468, MDA-MB-453 and SK-BR-3 cells [89]