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2011;50(7):499506 Lin, H.-C., Chen, Y.-F., Hsu, W.-H., Yang, C.-W., Kao, C.-H., and Tsai, T.-F

It also shows beneficial binding interactions with HGFs receptor, c-Met

Glutamate may affect the astrocytic swelling indirectly through the stimulation of neuronal activity, or directly via astrocytic glutamate receptors and transporters

Therefore, regulating abnormal lipid metabolism to target de novo FA synthesis and cholesterol biosynthesis is an important therapeutic strategy for HCC (145)

Mick et al., have recently reported that mitochondrial defects in the ETC can alter specific metabolites leading to activation of the ISR (117)

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