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Similar findings were discovered in preclinical animal models of lung cancer (199), in which most tumor-specific CD8+ T cells in the TDLNs are functional and exhibit a gene expression signature resembling that of stem-like CD8+ T cells (199), suggesting that the antigen presentation and T cell priming in TDLNs is critical for the ICB treatment

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Storage / Handling / Care Long-term Storage: Keep the lyophilized solid sealed at -20C until use

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