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Some PA patients appear to be able to respond to 'mega-doses' of oral B12 however, but this situation needs very careful management because it's not yet possible to work out who will benefit without a clinical trial

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found that donor pretreatment using a single dose of a small molecule inhibitor of FG-4497, an analog of roxadustat, significantly reduced the frequency of delayed graft function and markedly improved long-term outcome (Zhang et al., 2018)

20 mM), phosphate buffer of pH 5 (50 mM), hydrogen peroxide (40 mM), and 200 L enzyme extract

How will we monitor for both effectiveness and potential complications