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However, only pimitespib, an oral inhibitor developed by Taiho Pharmaceutical, was approved in Japan in 2022 for gastrointestinal stromal tumors, and it is currently the focus of a phase I study for the treatment of solid tumors in the EU and USA [7, 8]

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Effect of selenium on thyroid autoimmunity and regulatory T cells in patients with hashimotos thyroiditis: A prospective randomized-controlled trial

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Given that oxidative stress and inflammatory damage peak early in critical illness and trauma, delayed selenium administration may limit its protective effects

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