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Description

Here, Gln is decomposed into glutamate (Glu) and ammonia by the action of mitochondrial glutaminase

These processes are associated with midline frontal areas and dorsolateral prefrontal cortices (Muller-Oehring and Schulte, 2014)

doi: 10.1016/j.jpha.2022.11.004

Simultaneously targeting tissue transglutaminase and kidney type glutaminase sensitizes cancer cells to acid toxicity and offers new opportunities for therapeutic intervention