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Description

This heart rate elevation is believed to be mediated by direct GLP-1 receptor activation in the sinoatrial node and by sympathetic nervous system activation

They do nothing to address the underlying cause of pain

ChemBioChem 11 , 963971 (2010)

Following intraperitoneal dosing in rats and intravenous dosing in rabbits, maternal exposures were equivalent to 0.5, 1, or 2 times the human exposure at the therapeutic dose (based on AUC)