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Sikiric, P., Petek, M., Rucman, R., etal

It also inhibits the production of pro-inflammatory cytokines (TNF-, IL-6, excess TGF-) while stimulating anti-inflammatory cytokines (IL-10)

Oxidative stress is represented in the model by the concentration of H 2 O 2

Researchers have discovered a potent and selective glutamine transporter inhibitor, V9302, which specifically targets the SLC1A5 and effectively inhibits glutamine uptake [191].SLC1A5 has been reported to be involved in the modulation of the immune microenvironment in multiple types of tumors