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In particular, the Nf-B complex and the upstream proteins, as TRAF6, are negatively regulated by glutathione ( Glutathione plasmic levels and GP activity in patients with psoriasis were significantly lower than in general population ( Glutathione intracellular depletion in human antigen-presenting cells causes IL-10 production, with immuno-modulatory action, instead of the pro-inflammatory cytokines IL-12 and IL-23, responsible for Th1/Th17 immune system response switch in psoriasis

IF and IHC staining of tissue sections Tumour tissue sections were deparaffinized in Histo-Clear (Scientific Laboratory Supplies) for 5 min, rehydrated through a series of decreasing ethanol concentrations, followed by a final 5 min wash in distilled water (dH 2 O)

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[PubMed] [Google Scholar] 114.Vassallo P., Trohman R.G