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Mice The 6 to 8-week wild type (WT) mice on a C57BL/6J background, Rosa26-CAG-LSL-Cas9-tdTomato (tdTomato fl/fl , T002249), MANF fl/fl (for KI), MANF fl/fl (for KO), Alb-Cre, and 6-week male nude mice (BALB/c background) were purchased from GemPharmatech Co., Ltd (Nanjing, China)

Wang, K., Jia, F., Dang, W., Zhao, Y., Zhu, R., Sun, M., et al., J

Of the remaining follicles that were assessed, there was, however, a stark difference in their health, with a four-fold increase in the number of unhealthy primordial follicles with Dox treatment (Fig