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This pathway, termed TMED10-channeled unconventional protein secretion (THU), relies on the ERGIC-localized TMED10 protein to facilitate the entry of IL1 family factors into the secretory system, initiating unconventional secretion 17

doi: 10.1091/mbc.e08-12-1249 115 AxeELWalkerSAManifavaMChandraPRoderickHLHabermannAet al

Glaucoma is linked to degeneration of cortical and subcortical brain areas involved in vision and eye movements in addition to the loss of retinal ganglion cells [11]

Ive had Crohns disease for 13 years, and in that time, Ive experienced a variety of extraintestinal manifestations and side effects of living with this disease, but arguably none were more debilitating than my experience with a vitamin B-12 deficiency

Following the incubation time for each group, the cells were trypsinized, rinsed with PBS, and harvested