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10.1038/42408 121 SimonsK.IkonenE

The antioxidant activity of the Prdx system should be compromised when NADPH cannot be supplied by the pentose phosphate pathway

BertolloAGMingotiMEDPlissariMEBettiGJuniorWARLuzardoARet al

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This promoted the translocation of Bcl-2 to the outer mitochondrial membrane, where it interacted with voltage-dependent anion channel 1, inhibiting mitochondrial permeability transition pore (mPTP) opening