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Second, selective inhibition of mTORC1, without concurrent suppression of mTORC2, triggers compensatory activation of the PI3KAKT pathway via an S6K1IRS1 feedback loop, promoting cell survival rather than suppression

Because these codes are not available until November, we were unable to include them in the OPPS/ASC proposed rules

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Dysregulation of iron homeostasis by TfR-1 renders EZH2 wild type diffuse large B-cell lymphoma resistance to EZH2 inhibition

Badawy et al., 2002