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Participants were instructed to bring the samples to the study center within 6 h, where they were subsequently stored at 80 C until analysis [37]

Evidence limit These studies involved small sample sizes and short exposure periods

However, like any supplement, some people may experience mild side effects especially when starting out or taking high doses: Nausea or stomach upset: most common, usually passes after the first week Diarrhea or loose stools: reduce dose if this happens Fishy body odour: reported by some users, especially at high doses Headache: mild and temporary in some cases Restlessness or difficulty sleeping: avoid taking it late in the evening Safety Note: The European Food Safety Authority (EFSA) has declared L-carnitine safe at doses up to 3,000 mg/day for healthy adults

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mSphere (2016)