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For instance, 5-ASA derivatives, commonly used to treat UC, cost between $30 and $50 per month in African countries [43]

Therefore, it is possible to continuously generate a large amount of hydrogen in the large intestine, in which the environment is neutral to weakly alkaline, by oral administration of the Si-based agent

At once-weekly dosing, that is 20 to 40 weeks from a single vial

In postmarketing experience, postoperative hematomas and other signs of wound bleeding have been reported in association with the peri-operative use of IV or IM dosing of ketorolac tromethamine

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