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The expression of the remaining 18 genes, including ORC4 , BCL11B , and PAG1 , which were upregulated in the patients not treated with L-serine, was reduced following L-serine treatment

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This process not only enhances loading capacity but also improves retention, as the encapsulated molecules remain ion-trapped inside the vesicle

Treatment was administrated via tail vein injection every 3 days)

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