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Approximately one-fifth of individuals with PCT have an inherited UROD mutation and exhibit UROD activity at 50 % of normal in all tissues from birth

Dual beneficiaries had the highest proportion of claims with a NASH and NAFLD diagnoses

Moreover, ferroptosis plays an important role in the pathogenesis of liver diseases, with studies showing that acetaminophen (APAP)-induced ALF is related to ferroptosis[8]