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During active disease, UC is characterized by excessive activation of immune pathways and a surge in pro-inflammatory mediators

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Apoptosis 18 , 566577

[DOI] [PMC free article] [PubMed] [Google Scholar] 52.Goswami S, Raychaudhuri D, Singh P, Natarajan SM, Chen Y, Poon C, et al

Signals were filtered at 1 kHz using the amplifiers four-pole, low-pass Bessel filter, digitized with an Axon Digidata 1550B interface (Molecular Devices)

The reduced expression of CDK4 by EGCG, blocks the transition from G1 phase to S phase, which could cause a G0/G1 phase arrest of the cell cycle