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Loukas M, Tubbs RS, Mirzayan N, Shirak M, Steinberg A, Shoja MM

l-arginine depletion blunts antitumor T-cell responses by inducing myeloid-derived suppressor cells

BSA, bovine serum albumin

The transcriptional regulator CREB (cAMP response element binding protein) is a critical regulator of axonal growth and neuronal plasticity that is important for neuroprotection and cognition preservation [54]

20032006: Estudios fase I en humanos sanos

Because plasma tCys has been positively associated with fat mass in humans, we tested the hypothesis that decreased tCys in TgI278T Cbs / mice was the cause of the lean phenotype by placing the animals on water supplemented with N-acetyl cysteine (NAC) from birth to 240 days of age