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Using an established assay for CRISPR-based knock-in of sequences at the CLTA N-terminus (a highly expressed gene in HEK293T cells [Leonetti 2016] , neither our original split-wrmScarlet 11 sequence nor its mutant library enabled detectable complementation (Figure S10B, left panels)

97,98 Senescent T cells are characterized by a phenotypic shift with the downregulation of the costimulatory molecules CD27 and CD28 and the upregulation of the killer cell lectin-like receptor subfamily G and CD57

We would like to thank the students from the Department of Communication, Lauren Archibald '18, Brian Lloyd '18 and Daniel Valentino '17, along with their professor John Kilker, III for the production of this video

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No peptide has been studied for prevention in at-risk populations before symptom onset

(2/)ROS-targeting therapies were tested