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Cultures infected with Mtb secreted higher levels of TNF- and other cytokines [111]

Besides, recent works that also indicate that the excessive electron transport via l-GalLDH enzyme may affect other respiratory pathways

Knockdown of the cGAS-STING pathway prevented astrocyte senescence both in vitro and in vivo , thereby ameliorating Parkinson's disease-like pathology in MPTP-treated mice, a model that exhibits persistent Parkinsonian symptoms

For instance, excessive activation of PARP1 in response to chronic DNA damage and inflammation accelerates features of aging