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For example, parameters that have been shown in other studies to alter cecal and fecal microbiomes (e.g., vendor source 62,63 ) were consistent across experimental groups in this study

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routine B12 level monitoring is generally unnecessary once replacement is established, as levels do not reliably correlate with tissue stores Important safety considerations: Older adults may have impaired renal function, though this rarely affects B12 therapy given its wide safety margin