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In contrast, IFN- -deficient mice were less susceptible to alopecia areata (2)

J Neuroinflammation 9:275

Mitochondria-targeted FFa (Mito-FFa) increases the production of mtROS that triggers endoplasmic reticulum (ER) stress, and also oxidizes mtDNA and promotes its leakage into the cytoplasm

The canonical androgenic pathway (via AR/NR3C4) is crucial for the masculinization of zonation and the male-specific transcriptome of the adrenal 63,68,110