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Sex as a biological variable It is worth noting that although CYP1A2 activity is higher in men than in women, no significant gender differences in caffeine metabolism have been observed when assessed using urinary metabolite patterns or metabolite ratios [116]

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Two molecules of 3-hydroxy fatty acids are esterified to the glucosamine backbone of lipid A, and another two are connected via an amide linkage

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G.HochG.MakelaA.GuidolottiG.HeskelM.et al

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2.2.2.Glutathione (GSH) is synthesized in cells through a two-step enzymatic reaction facilitated by the enzyme Glutathione synthetase, which is often abbreviated as GshF

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Moreover, FSP1, which locates in the plasma membrane, prevents lipid peroxidation and inhibits ferroptosis even in the absence of GPX4 [56]

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