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The failure of these treatments to restore function and slow functional disease progression can be traced to their inability to correct the underlying cause of the dysfunction- diminished synaptic connectivity among neurons in the striatum and neuronal loss in the substantia nigra (SN)

Science 2014;344:630-4

Our previous studies have demonstrated that endogenous DA and DA-dependent neurodegeneration have a pathophysiologic role in sporadic as well as familial form of PD

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What the FDA's Rule Means for Compounded GLP-1 Access Will the rule mean that all access to compounded versions of GLP-1s will go away