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Inhibiting neuroinflammation As described above, chronic administration of APDs results in mitochondria dysfunction in neural cells of the brain, followed by oxidative stress and neuroinflammation, in which microglia, neurons, astrocytes, and peripheral immune cells work in hand with cytokines, chemokines, and the complement system to organize an inflammatory response

encapsulation of the drug within CrEL micelles, with the micelles acting as the principal carrier of paclitaxel in the systemic circulation

She skipped two entire dose escalation steps

(PubMed) Innis SM

Even though it causes shedding across the entire scalp, bitemporal hairs may be affected the most, as noted in the book Hair and Scalp Disorders