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3.1 Riboflavin transporter deficiency Riboflavin transporter deficiency (RTD)historically termed BrownVialettoVan Laere or Fazio-Londe syndromeis a rare, early-onset motor neuron disease that couples the biochemistry of riboflavin with overt neurodegeneration (12)

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However, the functions induced by these splice sites are not well defined and require further in-depth studies [77, 78]

5F and G), compared to the alcohol treatment group without YVAD, confirming that pyroptosis was not a part of the alcohol-induced cell death

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A number of residues within the loops around the putative substrate binding pocket (as illustrated in Fig