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Although cisplatin is a powerful anticancer medication, its clinical use is limited due to dose- and duration-dependent nephrotoxicity [1]

Inhibiting NNMT Expression Lowering the expression of the NNMT enzyme isnt anything new under the sun, as it is well-connected to several disease states: NNMT is implicated in various disease conditions such as metabolic disorders, neurodegenerative diseases and cancer, and tissue NNMT expression or plasma levels of its product MNA have been proposed as biomarkers for these conditions Other chronic metabolic diseases that are linked to NNMT expression include: Insulin resistance & diabetes Heart disease Kidney disease Liver disease Parkinsons disease Chronic inflammation Im not suggesting that 5-Amino 1MQ will directly lead to reducing your risk of any of the diseases above that time will come when researchers finally smarten up and start testing the peptide in human clinical trials

Blaser H, Dostert C, Mak TW, Brenner D

They make you look tired, older, and sometimes even unhealthyno matter how much sleep youve had

Targeting of CD163(+) macrophages in inflammatory and malignant diseases

Information of age of patients, Alanine transaminase (ALT) and Aspartate aminotransferase (AST) measurements, percentages of total protein and factor V is provided in table S6