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During check-ups, Dr

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The enzymes involved in these processes are dedicated oxidases (e.g., DsbAB system in bacteria, Ero1 and Erv1 in eukaryotic cells) and isomerases (e.g., DsbC/D system in bacteria, PDI in eukaryotic cells) [133]

In fibrotic lung tissue, TGF-1 expression is markedly elevated and contributes to the activation of fibroblasts into MYFs, increased synthesis of fibronectin, type I collagen, and -SMA, as well as promotion of EMT through canonical Smad-dependent signaling and non-canonical pathways [120, 121]

Additionally, the disordered nature of these regions may facilitate increased binding affinity[17].In conclusion, IDRs can serve as one of the primary criteria for assessing whether a molecule is capable of undergoing LLPS