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10.1038/nri3623 76 QuanY.GongL.HeJ.ZhouY.LiuM.CaoZ.et al (2019)

10.1111/j.1440-1746.2011.06756.x 102 ShiX.ZhaoY.DingC.WangZ.JiA.LiZ.et al (2018)

Cieslik KA, Sekhar RV, Granillo A, Reddy A, Medrano G, Heredia CP, et al

2007;42:798806 [6] Witting PK, Pettersson K, Letters J, Stocker R

El polipptido de FX modificado puede contener dos, tres, cuatro, cinco, seis, siete, ocho, nueve, diez o ms sustituciones de aminocidos, donde cada sustitucin se realiza en una posicin diferente, siempre que el polipptido de FX modificado resultante, cuando est en forma activa, presenta un aumento en la dependencia del cofactor y retiene una actividad cataltica dependiente de FVa