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doi: 10.1038/nrgastro.2016.191 192 PrietoG

Under normoxic conditions, this domain binds enzymes such as GAPDH and anchors them to the membrane, keeping their activity suppressed

These mutants couldnt survive in freshwater due to Na + /K + /Cl - uptake defects but thrived in brackish water, emphasizing PRLs vital role in ion balance (Shu et al., 2016)