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Melatonin can couple with CaM and suppresses ER--mediated functions by modulating the PKA-driven Ca 2+ /CaM pathway

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While senescent cells contribute to essential processes such as wound healing, their elimination may inadvertently hinder tissue regeneration and overall healing

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NMDA receptor antagonists, in contrast, work by reducing excitotoxicity, which can contribute to neuronal apoptosis and cognitive decline (Peng et al., 2023)