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4.5.2 Mechanism of action in dry eye disease Spermidine helps regulate the immune systems balance, crucial in conditions like DED, where inflammation plays a key role

Concurrently, DA markedly downregulates the anti-apoptotic proteins Bcl-2 and activates upstream signalling pathways, such as phosphorylated c-Jun N-terminal protein kinase (JNK) and ERK, collectively driving apoptosis in lung cancer cells [160]

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Attempts to create an HIV vaccine have been ongoing