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Isatuximab Isatuximab, developed by Sanofi, is the second CD38-targeting antibody approved by both the EMA and FDA in 2020/2021 for the treatment of MM

This iron effect on ERG production is consistent with a previous report using Methylobacterium species 27

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In some embodiments, the lipid particle also includes a targeting lipid described herein (e.g., the lipid particle consists essentially of a cationic lipid of formula I, a neutral lipid, a sterol, a PEG or PEG-modified lipid and a targeting moiety (e.g., GalNAc3-PEG-DSG))

Thus, in total we identified 30 interactions between 5 bacterial strains and 26 sweeteners and sugar substitutes (marked with * in Fig