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These components have applications in food, medicine, and cosmetics, such as the development of functional beverages, wound dressings, and anti-aging skincare products, reflecting the multidimensional value of Dioscorea opposita as food and medicine from the same source. Other Components of Dioscorea Opposita are summarized in Table 10

97, 98 Indeed, the RhoA/ROCK pathway has been shown to be involved in the formation of atherosclerotic lesions, vasoconstriction and myocardial hypertrophy and to be activated in patients with hypertension and in patients with coronary artery disease

BDNF is encoded by the BDNF gene located on chromosome 11 in humans, and the mature protein consists of 247 amino acids with a molecular weight of approximately 27 kDa

Mol Genet Metab 114(1):7379

Synthesis, biological evaluation, and molecular modeling studies of methylene imidazole substituted biaryls as inhibitors of human 17-hydroxylase-17,20-lyase (CYP17)part II: core rigidification and influence of substituents at the methylene bridge

[DOI] [PMC free article] [PubMed] [Google Scholar] 49.Waring AJ, Drake IM, Schorah CJ, et al